Common Precipitating Factors of Hepatic Encephalopathy in Patients of Chronic Liver Disease at Civil Hospital Karachi
نویسندگان
چکیده
OBJECTIVE: To determine frequency of common precipitating factors for Hepatic encephalopathy in chronic liver disease. PLACE AND DURATION OF STUDY: This study was conducted at Civil Hospital Karachi over a period of six months from June 2009 to December 2009. PATIENTS AND METHODS: This cross sectional study was conducted in Medical wards of Civil Hospital Karachi over a period of six months from June to December 2009. One hundred and ninety (n=190) adults including 98 (51.6% ) male and 92 (48.1 %) females, diagnosed cases of chronic liver disease were included in this study. Hepatic encephalopathy was diagnosed clinically on the basis of history, physical examination and relevant laboratory and radiological investigations. Data was analyzed on SPSS 16 and results were tabulated. RESULTS: A total number of one hundred and ninety (190) adult diagnosed cases of chronic liver disease, irrespective of cause were included in this study. Ninety eight (n= 98, 51.6%) were male and ninety two (92, 48.1 %) were females. The mean age was 52.35 years with STD ± 13.6. The common precipitating factors identified in this study were as follows. (n= 94,) (49.5 %) had constipation, (n=74, 38.9 % ) had infection, (n=74 , 38.9 %) had electrolyte imbalance, (n=70, 36.8 %) were on diuretic therapy, (n=62, 32.6 %) had hematemesis and melena, (n=52, 27.4%) had dehydration, (n=22, 11.6 % ) were on high protein diet and (n= 20, 10.5%) used sedatives. CONCLUSION: This study concludes that most common precipitating factors of hepatic encephalopathy in our set up are Constipation, Infection, Electrolyte imbalance and upper gastrointestinal bleeding... These factors are potentially preventable. A proper education and treatment plan in these patients can reduce the hospitalizations and overall morbidity and mortality.
منابع مشابه
Precipitating factors of hepatic encephalopathy in patients with chronic liver disease at Civil Hospital Karachi.
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